NJCC_05 v1 bwerk.indd
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چکیده
We report a case of a critically ill patient with a high anion-gap metabolic acidosis and liver failure due to chronic acetominophen use and alcohol abuse. The metabolic acidosis on admission was explained by the high lactate level, but further investigation showed high levels of pyroglutamic acid contributing to the metabolic acidosis. Withdrawal of acetominophen and treatment with N-acetylcysteine and haemofiltration lead to a rapid decline in pyroglutamic acid levels.
منابع مشابه
2007 NJCC_05 bwerk v1.indd
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متن کامل2007 NJCC_05 bwerk v1.indd
Infection of pancreatic and peripancreatic necrosis frequently complicates the course of severe acute pancreatitis and accounts for the majority of morbidity and mortality in these patients. Late infectious complications such as pancreatic abscesses appear less dangerous to the patient, but should be treated aggressively. The use of prophylactic broad spectrum antibiotics can no longer be suppo...
متن کاملNJCC_05 bwerk v1.indd
Prolonged administration of benzodiazepines and/or opioids to children in a pae diatric intensive care unit (PICU) may induce physiological depen dence and withdrawal symptoms. We reviewed the lit erature for relevant contributions on the nature of these withdrawal symptoms and on availability of valid scoring systems to assess the extent of symptoms in children. Symptoms of benzodiazepine and ...
متن کاملNJCC_06 v2 bwerk.indd
Oxidative stress derived from activated neutrophils is considered important in the development of multi-organ dysfunction syndrome during sepsis. However, so far, trials investigating the putative beneficial effects of antioxidant therapy have yielded conflicting results and have been subject to debate because of heterogenous patient populations and differences in the dosage and types of antiox...
متن کاملNJCC_01 v7 bwerk.indd
Fluid administration in critically ill patients is an important everyday therapeutic measure to improve organ perfusion. However, during the past decade, excessive fluid administration has been related to increased morbidity and mortality. This has led to the hypotheses that fluid administration without increasing cardiac output is inappropriate and is of no benefit to the patient. Over the pas...
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تاریخ انتشار 2008